Purine nucleotides
Apexbio Technology LLC Adenosine 58-61-7 1g
Adenosine (CAS 58-61-7) is a purine nucleoside consisting of adenine covalently linked to a ribose sugar via a -N9-glycosidic bond Endogenously adenosine modulates cellular signaling through activation of specific G protein-coupled adenosine receptors (A1 A2A A2B and A3) influencing diverse physiological processes such as neurotransmission vasodilation and immune responses In biomedical research adenosine is widely utilized to investigate purinergic signaling pathways cardiac function and the regulation of inflammatory and neuroprotective mechanisms as well as serving as a pharmacological tool in receptor binding and functional assays
Medchemexpress LLC Adenosine receptor antagonist 3 | 2400864-80-2 | 99.1% | 322.39 g/mol | C16H14N6S | 5 MG
Adenosine receptor antagonist 3 is a small-molecule research compound used to study adenosine receptor pharmacology. It is provided in small milligram quantities for in vitro biochemical and pharmacological studies and is characterized by a molecular formula of C16H14N6S and a molecular weight of 322.39 g/mol.
- Supplied as a light yellow to yellow solid.
- Molecular formula C16H14N6S and molecular weight 322.39 g/mol.
- Reported purity approximately 99.1%.
- Available in small pack sizes including 5 mg, 10 mg, 25 mg, and 100 mg.
- Powder storage: -20°C (stable for 3 years) or 4°C (stable for 2 years); in solvent: -80°C (6 months) or -20°C (1 month).
- For in vitro research use only; not for human or diagnostic use.
Apexbio Technology LLC 8-Aza-ATP 50ul (100 mM)
8-Aza-ATP is a structural analog of ATP characterized by the substitution of the carbon atom at the 8-position of the purine ring with nitrogen resulting in an 8-azapurine nucleotide moiety Due to this structural alteration 8-Aza-ATP competitively interacts with ATP-binding sites on enzymes thereby modulating their catalytic activities This compound serves as a tool in biochemical research to elucidate enzyme-substrate recognition nucleotide binding specificity and catalytic mechanisms of ATP-dependent enzymes Additionally it is utilized in the study of cellular energy metabolism signal transduction pathways and nucleotide-mediated regulatory processes contributing to understanding relevant physiological and pathological mechanisms
Medchemexpress LLC Guanosine triphosphate trisodium salt | 36051-31-7 | 589.13 | 1 ML
Guanosine triphosphate trisodium salt, 100 mM Solution, PCR Grade is a solution prepared from guanosine triphosphate at a concentration of 100 mM. It is free of DNase, RNase, and phosphatase contamination, making it suitable for various molecular biology research applications.
- Prepared from guanosine triphosphate at 100 mM concentration.
- Free of DNase contamination.
- Free of RNase contamination.
- Free of phosphatase contamination.
- Suitable for molecular biology research.
Medchemexpress LLC Adenosine 5'-phosphosulfate (disodium) | 102029-95-8 | 97.0% | 471.25 | 1 MG
Adenosine 5'-phosphosulfate disodium is a metabolism intermediate of sulfur. It can be used to study sulfotransferases and sulforeductases in various organisms.
- For research use only.
- Not sold to patients.
Medchemexpress LLC Guanosine, 6-O-methyl- | 7803-88-5 | 99.7% | 297.27 | 100 MG
6-O-Methyl Guanosine is a modified nucleoside that inhibits colony-forming ability in a malignant xeroderma pigmentosum cell line.
- Modified nucleoside
- Inhibits colony-forming ability in a malignant xeroderma pigmentosum cell line
- For research use only
Medchemexpress LLC Guanosine, 6-O-methyl- | 7803-88-5 | 99.7% | 297.27 | 25 MG
6-O-Methyl Guanosine is identified as a modified nucleoside. Research indicates its capacity to inhibit the colony-forming ability in a malignant xeroderma pigmentosum cell line, suggesting potential applications in cell biology studies related to cell proliferation and specific genetic disorders. This modified nucleoside provides a tool for investigating cellular mechanisms and could contribute to understanding pathways involved in malignancy.
- Modified nucleoside.
- Inhibits colony-forming ability in a malignant xeroderma pigmentosum cell line.
Medchemexpress LLC Guanosine 5'-triphosphate trisodium salt hydrate | 207300-85-4 | 95.0% | 500 MG
Guanosine 5'-triphosphate trisodium salt hydrate activates signal transducing G proteins and functions as an energy-rich precursor for mononucleotide units in the enzymatic biosynthesis of DNA and RNA. This product is intended for research use only.
- Activates signal transducing G proteins
- Precursor for DNA and RNA biosynthesis
- Solid, white to off-white physical form
- Store at -20°C under nitrogen, away from moisture
- When in solvent, stable at -80°C for 6 months and -20°C for 1 month
- Soluble in H2O at ≥ 150 mg/mL
Medchemexpress LLC Guanosine 5'-triphosphate trisodium salt hydrate | 207300-85-4 | 95.0% | 100 MG
Guanosine 5'-triphosphate trisodium salt hydrate is an activator of the signal transducing G proteins and serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
- Activator of signal transducing G proteins
- Energy-rich precursor in DNA and RNA biosynthesis
- For research use only
Medchemexpress LLC GTP-14564 | 34823-86-4 | 99.9% | 234.25 | 10 MG
GTP-14564 is a tyrosine kinase inhibitor that targets internal tandem duplication (ITD) and FLT3. It inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
- Tyrosine kinase inhibitor
- Targets ITD and FLT3
- Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells
- Available in various quantities
- Available as solid or in solution (10 mM in DMSO)
- Off-white to yellow solid appearance
- For research use only
- Has a data sheet, COA, SDS, and handling instructions available
Medchemexpress LLC GTP-14564 | 34823-86-4 | 99.9% | 234.25 | 25 MG
GTP-14564 is a tyrosine kinase inhibitor that targets internal tandem duplication (ITD) and FLT3. It inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
- Tyrosine kinase inhibitor
- Targets ITD and FLT3
- Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells
Medchemexpress LLC Adenosine | 58-61-7 | 100.0% | 50 G
Adenosine is a ubiquitous and BBB-permeable endogenous autacoid, acting through four G protein-coupled receptors (A1, A2A, A2B, and A3). It influences nearly all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation. As an extracellular signaling molecule derived from 5'-adenosine triphosphate (ATP) and 5'-adenosine monophosphate (AMP), it plays a critical role in cellular processes.
- Influences neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
- Acts via G protein-coupled receptors: A1, A2A, A2B, and A3.
- Inhibits cell viability and triggers ER stress in HepG2 cells at high concentrations.
- Induces apoptosis and autophagy in HepG2 cells via the AMPK/mTOR pathway.
Medchemexpress LLC Adenosine-13C5 | 159496-13-6 | 99.9% | 1 MG
Adenosine-13C5 is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
- Isotope-labeled compound, incorporating a stable heavy isotope of carbon (13C).
- Used as a tracer and internal standard for quantitative analysis by techniques like NMR, GC-MS, or LC-MS.
- Plays a crucial role in various cellular physiological processes.
- Purity of 99.9%.
- Appears as a white to off-white solid.
- Soluble in DMSO (33.33 mg/mL) and H2O (≥ 6.67 mg/mL).
- Recommended storage as a powder at -20°C for 3 years or 4°C for 2 years.
- In solvent, recommended storage at -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC Adenosine (Standard) | 58-61-7 | 99.39% | 50 MG
Adenosine (Standard) is the analytical standard of Adenosine, intended for research and analytical applications. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. It affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
- Analytical standard for research and analytical applications
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for techniques such as HPLC, GC, and MS